Wine Country A 2 1/2-hour drive north from Santiago leads to the heart of Chilean wine culture, Colchagua Valley. More than 30 wineries are scattered among the region’s colonial towns and haciendas, including Emiliana Orgánico. The most stunning of all is Clos Apalta, a new winery in the micro-valley of Apalta. With its rounded wood exterior and spiraling staircase, the structure resembles a deconstructed wine barrel. Clos Apalta shares a woody hillside with the Lapostolle Residence (doubles from $650, including meals and tour), just four 1,000-square-foot casitas with exposed beams and Cambodian silk curtains. For dinner, head to the nearby Asador del Valle (dinner for two $40), a rustic restaurant where three chef brothers roast Patagonia lamb whole on the spit.